PYRROLIDINE-1-SULFONYL CHLORIDE

PYRROLIDINE-1-SULFONYL CHLORIDE - Names and Identifiers

Name	pyrrolidine-1-sulfonyl chloride
Synonyms	Albb-005584 1-PyrrolidinesulfonylChloride 1-pyrrolidinesulfonyl chloride PYRROLIDINE-1-SULFONYL CHLORIDE pyrrolidine-1-sulfonyl chloride
CAS	1689-02-7
InChI	InChI=1/C4H8ClNO2S/c5-9(7,8)6-3-1-2-4-6/h1-4H2

PYRROLIDINE-1-SULFONYL CHLORIDE - Physico-chemical Properties

Molecular Formula	C4H8ClNO2S
Molar Mass	169.63
Density	1.48±0.1 g/cm3(Predicted)
Boling Point	65-75 °C(Press: 0.2 Torr)
Flash Point	109.5°C
Vapor Presure	0.0145mmHg at 25°C
pKa	-8.42±0.20(Predicted)
Storage Condition	-20℃
Refractive Index	1.542

PYRROLIDINE-1-SULFONYL CHLORIDE - Risk and Safety

Hazard Class

IRRITANT

PYRROLIDINE-1-SULFONYL CHLORIDE - Introduction

pyrrolidine-1-sulfonyl chloride is an organic compound with the chemical formula C4H4ClNO2S. The following is a description of the nature, use, formulation and safety information of pyrrolidine-1-sulfonyl chloride:

Nature:
- pyrrolidine-1-sulfonyl chloride is a colorless to pale yellow liquid with a strong pungent odor.
-It is an electrophilic chlorination reagent, which is heated and decomposed in water to generate harmful gases.
-It has strong oxidation and can react with water to generate sulfuric acid and hydrogen chloride.

Use:
- pyrrolidine-1-sulfonyl chloride is commonly used as a chlorination reagent in organic synthesis, and can be used to introduce sulfonyl chloride groups to generate various functional compounds.
-It can be used to prepare pyrrolidine -1-sulfonamide compounds and used as an important intermediate in drug synthesis.

Method:
- pyrrolidine-1-sulfonyl chloride is usually prepared by reacting pyrrolidine-1-sulfonylfolylamine with thionyl chloride.

Safety Information:
- pyrrolidine-1-sulfonyl chloride is irritating and can cause burns in contact with skin and eyes. Direct exposure should be avoided.
-Wear protective gloves, safety glasses, and a lab coat when using or handling pyrrolidine-1-sulfonyl chloride.
- pyrrolidine-1-sulfonyl chloride is potentially harmful to the environment, it should be avoided from being discharged into water or soil.
-When storing, keep the pyrrolidine-1-sulfonyl chloride in a dry, low temperature and well ventilated place, away from fire and oxidizing agents.

Please note that this is only a general description of the pyrrolidine-1-sulfonyl chloride, and specific properties, uses and safety information may require reference to the chemical literature in greater detail. When using pyrrolidine-1-sulfonyl chloride, be sure to observe proper laboratory practices and safety measures.

Last Update：2024-04-09 15:17:53